P4028 - Bariatric Surgery and Hospitalization Outcomes in Acute Pancreatitis: Mortality, Costs, and Weight Loss Effects

Chun-Wei Pan, MD¹, Neethi Dasu, DO², David Truscello, DO², Muhammad Bilal Ibrahim, MD^1
1John H. Stroger, Jr. Hospital of Cook County, Chicago, IL; ²Jefferson Health, New Jersey, NJ

Introduction: Obesity is a global epidemic, thus translating to an increased number of bariatric surgeries performed worldwide. Prior research has established that bariatric surgery can improve the metabolic profile and reduce inflammation seen in obesity. Both obesity and bariatric surgery are known risk factors for acute pancreatitis. In this study, we aimed to explore the effect of prior bariatric surgery on hospitalization outcomes with a diagnosis of acute pancreatitis.

Methods: We utilized the National Inpatient sample database between the years 2016-2020. Adult patients with a diagnosis of Acute pancreatitis were identified. The exposed group was defined as Pancreatitis with a history of bariatric surgery, and the unexposed group as acute pancreatitis with morbid obesity. We further analyzed the exposed group according to BMI (< 35 kg/m2 and >35 kg /m2) to explore the effect of prior bariatric surgery on successful weight loss.

Results:

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  We found 2,201,599 morbidly obese and 45,355 bariatric surgery patients. Mortality rate was significantly lower in the bariatric surgery group (0.7% vs. 2.0%, aOR 0.5, P< 0.01) as were total charges by $7,563.90 and LOS by 0.6 days (P< 0.01). This group also showed lower composite complication rates (aOR: 0.6; P< 0.01).
  
  


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  Subgroup analysis in BMI >35 kg/m2 patients showed no mortality rate difference (aOR 0.8, P=0.16), but significantly less LOS (0.6 days less, P< 0.01) and charges ($9,160 less, P< 0.01).
  
  


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  Bariatric patients with successful weight loss had lower mortality odds (aOR 0.3, P=0.005), shorter LOS (1.3 days less, P< 0.05), and lower charges ($18,792 less, P< 0.05). However, no significant difference was noted in complication rates (aOR 0.9, P=0.26).
  
  

Discussion: Our study highlights the benefits of prior bariatric surgery in patients with acute pancreatitis. We observed lower mortality rates, reduced hospital charges, and shorter hospital stays in patients with a history of bariatric surgery. These advantages extended to patients with a BMI >35 kg/m2 and those achieving successful weight loss through post-surgery. Our findings highlights the potential role of bariatric surgery in enhancing patient outcomes and reducing healthcare costs. Future studies should further explore these impacts.


Disclosures:


Chun-Wei Pan, MD¹, Neethi Dasu, DO², David Truscello, DO², Muhammad Bilal Ibrahim, MD¹. P4028 - Bariatric Surgery and Hospitalization Outcomes in Acute Pancreatitis: Mortality, Costs, and Weight Loss Effects, ACG 2023 Annual Scientific Meeting Abstracts. Vancouver, BC, Canada: American College of Gastroenterology.