Louisiana State University Health Sciences Center Lafayette, LA
Ali K. Yousuf, DO, Farha Khan, MD Louisiana State University Health Sciences Center, Lafayette, LA
Introduction: Neuroendocrine tumors (NETs) represent a diverse group of neoplasms originating from neuroendocrine cells. They can arise in various organs throughout the body, including the gastrointestinal tract. Gastric NETs are relatively uncommon, accounting for a small percentage of all gastric tumors. We describe a case in which gastric NETs were incidentally discovered during gastric bypass surgery, emphasizing the significance of early detection and appropriate management in such cases.
Case Description/Methods: A 39-year-old female with a history of morbid obesity presented to our surgical department for a laparoscopic gastric bypass procedure. Preoperative evaluation, including routine laboratory tests and imaging studies, did not reveal any significant abnormalities. During the surgical procedure, multiple small nodules were incidentally identified in the gastric mucosa. Intraoperative frozen section analysis confirmed the presence of multiple neuroendocrine tumors. Follow-up visits were scheduled at regular intervals, including upper gastrointestinal endoscopy, abdominal CT scans, and tumor marker assessments. The patient remains under surveillance, with no evidence of tumor recurrence or metastasis during the 6-month follow-up period.
Discussion: Gastric neuroendocrine tumors are a rare entity, and their incidence is increasing. The incidental discovery of these tumors during gastric bypass surgery highlights the importance of a thorough preoperative evaluation and endoscopic examination. Early diagnosis and appropriate management can lead to favorable outcomes. Surgical resection remains the mainstay of treatment for localized disease, while multimodal approaches are considered for advanced cases. Further studies are warranted to better understand the underlying pathogenesis, prognostic factors, and therapeutic options for these rare tumors.
Disclosures:
Ali Yousuf indicated no relevant financial relationships.
Farha Khan indicated no relevant financial relationships.
Ali K. Yousuf, DO, Farha Khan, MD. P4199 - The Tummy's Secret: Unmasking Neuroendocrine Tumors During Gastric Bypass Surgery, ACG 2023 Annual Scientific Meeting Abstracts. Vancouver, BC, Canada: American College of Gastroenterology.
