Medicine Institute, Allegheny Health Network Pittsburgh, Pennsylvania
Mohammad Aldiabat, MD1, Muhammad Ali Butt, MD2, Tyrell Daniel, MD3, Balaji Jagdish, DO3, James Rock III, DO3, Aarushi Sudan, MD4, Majd Al-ahmad, MD5, Saba Altarawneh, MD6, Saqr Alsakarneh, MD7, Ahmad Jabri, MD8, Laith Alhuneafat, MD9 1NYU Langone, New York, NY; 2Medicine Institute, Allegheny Health Network, Pittsburgh, PA; 3Allegheny General Hospital, Pittsburgh, PA; 4Jacobi Medical Center, New York, NY; 5University of Pittsburgh Medical Center, Pittsburgh, PA; 6Marshall University, Huntington, WV; 7University of Missouri-Kansas City, Kansas City, MO; 8Metro Health Medical Center, Cleveland, OH; 9Allegheny Health Network, Pittsburgh, PA
Introduction: While both inflammatory bowel disease (IBD) and COVID-19 are known to independently increase the risk of gastrointestinal bleeding, venous thromboembolism, and mortality, the comparative risk for COVID-19 patients with IBD as compared to non-IBD patients is not well described.
Methods: We used the National Inpatient Sample from January to December 2020. To investigate inpatient outcomes seen in ulcerative colitis (UC) and Crohn’s disease (CD) after contracting COVID-19 compared to non-IBD patients. We excluded those less than 18 years of age. Inpatient outcomes were compared in IBD and non-IBD COVID cohorts.
Results: Out of 1,050,045 COVID-19 hospitalizations, 0.28% had CD (2,954) and 0.26% had UC (2,794). UC patients had a higher risk of DVT with an adjusted odds ratio of 2.55 (p< 0.001), while CD patients did not show a significant association with DVT (aOR ratio of 1.29, p=0.329) and neither UC nor CD were associated with PE. The study found no significant difference in non-variceal GIB incidence or in-hospital mortality between the groups studied. UC patients had a longer average hospital stay (8.25 days) than non-IBD patients (aMD 0.89, p-value 0.007), but no significant differences were observed between CD patients and non-IBD patients. Healthcare resource utilization between the three groups was comparable.
Discussion: In our nationally representative study of COVID-19 hospitalizations, IBD patients had similar rates of GIB, PE, and mortality to non-IBD patients. UC patients had a higher likelihood of developing DVT. Further research is needed to fully understand the relationship between IBD and COVID-19.
Disclosures:
Mohammad Aldiabat indicated no relevant financial relationships.
Muhammad Ali Butt indicated no relevant financial relationships.
Tyrell Daniel indicated no relevant financial relationships.
Balaji Jagdish indicated no relevant financial relationships.
James Rock III indicated no relevant financial relationships.
Aarushi Sudan indicated no relevant financial relationships.
Majd Al-ahmad indicated no relevant financial relationships.
Saba Altarawneh indicated no relevant financial relationships.
Saqr Alsakarneh indicated no relevant financial relationships.
Ahmad Jabri indicated no relevant financial relationships.
Laith Alhuneafat indicated no relevant financial relationships.
Mohammad Aldiabat, MD1, Muhammad Ali Butt, MD2, Tyrell Daniel, MD3, Balaji Jagdish, DO3, James Rock III, DO3, Aarushi Sudan, MD4, Majd Al-ahmad, MD5, Saba Altarawneh, MD6, Saqr Alsakarneh, MD7, Ahmad Jabri, MD8, Laith Alhuneafat, MD9. P0785 - Outcomes of COVID-19 In-patients With Inflammatory Bowel Disease: A Nationwide Analysis, ACG 2023 Annual Scientific Meeting Abstracts. Vancouver, BC, Canada: American College of Gastroenterology.
