P1940 - The Burden and Hospital-Based Outcomes of Ogilvie Syndrome in the US Population in 2020

Zahid Ijaz Tarar, MD¹, Umer Farooq, MD², Mustafa Gandhi, MD³, Saad Saleem, MD⁴, Hamza Ertugrul, MD⁵, Ebubekir Daglilar, MD^6
1University of Missouri, School of Medicine, Columbia, MO; ²Saint Louis University, St. Louis, MO; ³University of Missouri-Columbia, Columbia, MO; ⁴Sunrise Hospital and Medical Center, Los Vegas, NV; ⁵University of Missouri, Columbia, MO; ⁶Charleston Area Medical Center, West Virginia University School of Medicine, Charleston, WV

Introduction: Ogilvie’s syndrome described as pseudo-obstruction of the colon consists of dilatation of the colon and rectum without mechanical obstruction. There is a poor understanding of the etiopathogenesis of Ogilvie syndrome with limited treatment options. In our study, we determined the prevalence and outcome of Ogilvie syndrome hospitalization in the US population in the year 2020.

Methods: Using the National inpatient sample 2020, we included the patients who were admitted for Ogilvie syndrome. International Classification of disease tenth revision (ICD-10) was used to select the study population Our outcome of interest was all-cause inpatient mortality, sepsis, ICU admission, peritonitis, bowel ischemia, bowel perforation, and hospital resource utilization.

Results: A total of 2650 patients with a principal diagnosis of Ogilvie syndrome were admitted in 2020. The mean age of study patients was 67.7 years, and 34.1% were females. The overall mortality rate was 9.2% (95% CI 7.6%- 11.1%). The rate of other complications was as follows; Sepsis 17.1% (95% CI 15%-19.4%), ICU admissions 10.7% (95% CI 9.1%-12.7%), Bowel perforation 1.8% (1.1%-2.7%), Peritonitis 1.9% (95% CI 1.3%-2.7%), Bowel Ischemia (0.6% 95% CI 0.3%-1.3%). Among these patients, 11.8% of them received colonoscopy for decompression, whereas 0.16% underwent cecal resection. The average length of stay was 12.8 days (95% CI 11.9 days-13.7 days), and the mean hospitalization cost was 37,517 $ (95% CI 34,500$- 40,735$). (Table 1).

Discussion: Although Ogilvie’s syndrome is an uncommon condition, it is associated with a prolonged hospital stay and increased costs. It is important to diagnose it early and manage it appropriately to prevent worse outcomes. New treatment options are needed to adequately manage this condition.


Disclosures:


Zahid Ijaz Tarar, MD¹, Umer Farooq, MD², Mustafa Gandhi, MD³, Saad Saleem, MD⁴, Hamza Ertugrul, MD⁵, Ebubekir Daglilar, MD⁶. P1940 - The Burden and Hospital-Based Outcomes of Ogilvie Syndrome in the US Population in 2020, ACG 2023 Annual Scientific Meeting Abstracts. Vancouver, BC, Canada: American College of Gastroenterology.