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Monday Poster Session

Category: IBD

P2197 - Cannabis Use in Patients With Inflammatory Bowel Disease Creates Significantly Greater Resource Utilization During Endoscopy

Monday, October 23, 2023
10:30 AM – 4:15 PM PT
Location: Exhibit Hall
Has Audio
Lauren Loeb, MD1, Alexander Hochwald, BS1, Michael F.. Picco, MD, PhD, FACG1, Johanna Chan, MD1, Jana G.. Hashash, MD, MSc, FACG2, Ryan Chadha, MD1, Francis A. Farraye, MD, MSc, MACG2, Jami Kinnucan, MD, FACG1
1Mayo Clinic Florida, Jacksonville, FL; 2Mayo Clinic, Jacksonville, FL

Introduction: Patients with inflammatory bowel disease (IBD) often experience abdominal pain and decreased appetite that can be refractory to presently available treatments, prompting use of complimentary and alternative therapies such as cannabis. Previous studies have shown that cannabis users require higher levels of sedation for procedures. We aim to investigate if patients with IBD who report cannabis use require more resources for endoscopic procedures including propofol sedation, length of procedure, and post-procedural recovery.

Methods: A retrospective case-control study of adult patients with IBD between November 2018 and November 2022 at a Tri-state tertiary academic medical center undergoing endoscopic evaluation. Cases were matched for age, sex, and body mass index. Continuous variables were compared with a Kruskal-Wallis test and categorical variables were compared with Fisher’s exact test.

Results: There were 124 patients with IBD included with 62 patients reporting cannabis use and 62 patients without cannabis use. There was a significant difference in total propofol dose administered (p < 0.001) and duration of endoscopy (p < 0.001) between patients who reported cannabis use and those that did not. There was no significant difference in length of stay in the recovery room between the two groups (p = 0.15).

Discussion: In this study, patients with IBD who report cannabis use have a longer duration of endoscopy and require higher doses of propofol to maintain sedation compared to those who did not report cannabis use. Our study underscores the importance of medication reconciliation and patient disclosure of complimentary and alternative medicines to allow for more accurate scheduling and resource allocation.


Disclosures:
Lauren Loeb indicated no relevant financial relationships.
Alexander Hochwald indicated no relevant financial relationships.
Michael Picco indicated no relevant financial relationships.
Johanna Chan indicated no relevant financial relationships.
Jana Hashash: Iterative Health – Grant/Research Support.
Ryan Chadha indicated no relevant financial relationships.
Francis Farraye: AbbVie – Advisory Committee/Board Member. Avalo Therapeutics – Advisory Committee/Board Member. BMS – Advisory Committee/Board Member. Braintree Labs – Advisory Committee/Board Member. Fresenius Kabi – Advisory Committee/Board Member. GI Reviewers – Independent Contractor. GSK – Advisory Committee/Board Member. IBD Educational Group – Independent Contractor. Iterative Health – Advisory Committee/Board Member. Janssen – Advisory Committee/Board Member. Pfizer – Advisory Committee/Board Member. Pharmacosmos – Advisory Committee/Board Member. Sandoz Immunology – Advisory Committee/Board Member. Sebela – Advisory Committee/Board Member. Viatris – Advisory Committee/Board Member.
Jami Kinnucan: Abbvie – Advisory Committee/Board Member, Consultant. BMS – Advisory Committee/Board Member, Consultant. Fresinius kabi – Advisory Committee/Board Member, Consultant. Janssen – Advisory Committee/Board Member. Pfizer – Advisory Committee/Board Member, Consultant. Takeda – Advisory Committee/Board Member, Consultant.


Lauren Loeb, MD1, Alexander Hochwald, BS1, Michael F.. Picco, MD, PhD, FACG1, Johanna Chan, MD1, Jana G.. Hashash, MD, MSc, FACG2, Ryan Chadha, MD1, Francis A. Farraye, MD, MSc, MACG2, Jami Kinnucan, MD, FACG1. P2197 - Cannabis Use in Patients With Inflammatory Bowel Disease Creates Significantly Greater Resource Utilization During Endoscopy, ACG 2023 Annual Scientific Meeting Abstracts. Vancouver, BC, Canada: American College of Gastroenterology.