Yuhan Fu, DO1, Gengqing Song, MD2 1University of Louisville, Louisville, KY; 2MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH
Introduction: Gastric cancer is the fifth leading cause of cancer worldwide. The highest incidence was observed in East Asia, Central and South America, and Eastern Europe. The incidence of gastric cancer is higher in males than in females. The aim of the study was to determine the prevalence and incidence of gastric cancer in different genders and races from 2005 to 2022.
Methods: We performed a retrospective population-based study using TriNetX, a global federated research network with over 120 million patients. We determined the prevalence and incidence of gastric cancer among patients who completed an Esophagogastroduodenoscopy (EGD) from 2005 to 2022. Patients were subsequently stratified based on gender and race. Prevalence and incidence were determined respectively.
Results: Our results showed that the incidence of gastric cancer has been increasing from 2005 to 2022: from 67 to 206 cases/100,000 person-year. The prevalence of gastric cancer increased from 0.26% to 0.97% from 2005 to 2022. We observed similar trends in both females and males. The incidence rates increased from 41 to 122 cases/100,000 person-year in females and from 104 to 331 cases/100,000 person-year in males. The prevalence of gastric cancer increased from 0.17% to 0.62% in females, and from 0.39% to 1.45% in males. The incidence rates and prevalence of gastric cancer are higher in males than in females. Incidence and prevalence of gastric cancer were increasing since 2005 and remained the highest among Asian population with an incidence rate of 338 cases/100,000 person-year. The incidence of gastric cancer in American Indian or Alaska Native has been rapidly increasing since 2014-2016 and became the second highest in 2020-2022 with 271 cases/100,000 person-year. The incidence of gastric cancer in Native Hawaiian or Other Pacific Islander was the third highest and was plateauing around 226 cases/100,000 person-year in 2020-2022. The incidence of gastric cancer was plateauing among African American and Caucasian.
Discussion: The incidence and prevalence of gastric cancer are increasing from 2005 to 2022. The incidence and prevalence of gastric cancer are higher in males than in females. Asian population has the highest incidence and prevalence of gastric cancer.
Figure: Figure 1 A: Incidence of gastric cancer in different genders. B: Incidence of gastric cancer in different races
Disclosures:
Yuhan Fu indicated no relevant financial relationships.
Gengqing Song indicated no relevant financial relationships.
Yuhan Fu, DO1, Gengqing Song, MD2. P2739 - Epidemiology Updates of Gastric Cancer: A Global Healthcare Database Study, ACG 2023 Annual Scientific Meeting Abstracts. Vancouver, BC, Canada: American College of Gastroenterology.
